Across TCGA patient cohorts, UGT2B11 mutation is significantly associated with the RNA expression of many other genes, with 2,898 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UGT2B11-associated genes across cancer lineages are MRPS15, HMG20B, and PYCR1. Each is linked with UGT2B11 in more than 3 cancer types. Because this analysis shows association rather than direction, both UGT2B11-to-partner and partner-to-UGT2B11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B11→partner) and Y-score (partner→UGT2B11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPS15 →	+0.426	+4.021	.005	<.001	3	4
SKCM	HMG20B →	+0.489	+1.803	<.001	<.001	3	3
SKCM	PYCR1 →	+0.413	+2.682	.008	<.001	3	3
SKCM	FBXL15 →	+0.301	+1.616	.006	<.001	3	3
UCEC	MRPL37 →	+0.485	+3.748	.004	<.001	3	3
SKCM	AGBL5 →	+0.332	+2.488	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,898 associations by consensus.

Exploration

UGT2B11 survival (RNA) · tumor vs normal (RNA) · all UGT2B11 data types