Across TCGA pan-cancer cohorts, UGT2B11 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated UGT2B11 data layer compared with 6 for mutation status.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher UGT2B11 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated UGT2B11 expression acts as an unfavorable survival marker, although some lineages such as ACC and READ show a favorable association.
ACC, READ, and THCA are the cancer types where UGT2B11 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.