UGT2B11

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UGT2B11 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UGT2B11-associated genes across cancer lineages are Src, ACC_pS79, and INPP4B. Each is linked with UGT2B11 in more than 2 cancer types. Because this analysis shows association rather than direction, both UGT2B11-to-partner and partner-to-UGT2B11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B11→partner) and Y-score (partner→UGT2B11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMSrc →-0.149-1.584.039.03233
UCECACC_pS79 →+0.392+2.000.012.03232
UCECINPP4B →-0.349-3.169.016.01832
UCECATM →-0.638-3.308.001.00932
SKCMTransglutaminase →-0.128-2.222.022.00832
LUADRAD51 →+0.388+2.824<.001.03631
Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

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