Across TCGA cell cohorts, UGT2B11 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UGT2B11-associated genes across cancer lineages are VE-822, AZD5153, and GSK2110183B. Each is linked with UGT2B11 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT2B11-to-partner and partner-to-UGT2B11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B11→partner) and Y-score (partner→UGT2B11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	VE-822 →	+0.601	+2.646	.036	.047	3	1
LARGE_INTESTINE	AZD5153 →	+0.584	+2.649	.020	.046	3	1
LARGE_INTESTINE	GSK2110183B →	+0.633	+2.649	.037	.046	3	1
LARGE_INTESTINE	Dactinomycin →	+0.511	+2.649	.029	.046	3	1
LARGE_INTESTINE	50869 →	+0.482	+2.649	.022	.046	3	1
LARGE_INTESTINE	Sabutoclax →	+0.424	+2.769	.046	.040	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

UGT2B11 survival (RNA) · tumor vs normal (RNA) · all UGT2B11 data types