UGT2B10

Across TCGA cell cohorts, UGT2B10 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible UGT2B10-associated genes across cancer lineages are CRYBB1, OR2T33, and SIGLECL1. Each is linked with UGT2B10 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT2B10-to-partner and partner-to-UGT2B10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYBB1 grouped by UGT2B10-low versus UGT2B10-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B10→partner) and Y-score (partner→UGT2B10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CRYBB1 →	+0.186	+3.781	.001	.009	3	1
BREAST	OR2T33 →	+0.098	+3.807	.004	.003	3	1
BREAST	SIGLECL1 →	+0.013	+3.781	<.001	.009	3	1
BREAST	SERPINB11 →	+0.042	+3.415	<.001	.004	3	1
CNS	TAAR6 →	+0.022	+5.321	<.001	.005	3	1
CNS	FAM240B →	+0.098	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

CRYBB1 by UGT2B10 expression — BREAST

Explore this box plot interactively →