UGP2

Across TCGA cell cohorts, UGP2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible UGP2-associated genes across cancer lineages are TBC1D3 and SIGLEC12. Each is linked with UGP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGP2-to-partner and partner-to-UGP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D3 grouped by UGP2-low versus UGP2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGP2→partner) and Y-score (partner→UGP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D3 →	+0.061	+3.688	<.001	.002	3	1
BREAST	SIGLEC12 →	+0.030	+4.025	.007	.009	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TBC1D3 by UGP2 expression — LARGE_INTESTINE

Explore this box plot interactively →