UGGT2

Across TCGA patient cohorts, UGGT2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,205 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UGGT2-associated genes across cancer lineages are CD276, RUNX2, and FKBP10. Each is linked with UGGT2 in more than 5 cancer types. Because this analysis shows association rather than direction, both UGGT2-to-partner and partner-to-UGGT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UGGT2 versus CD276 in COAD, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGGT2→partner) and Y-score (partner→UGGT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CD276 →	+0.742	+0.415	<.001	.005	3	6
UCEC	RUNX2 →	+1.139	+0.294	<.001	<.001	3	6
LUAD	FKBP10 →	+1.308	+0.316	<.001	<.001	3	6
GBM	COL1A1 →	+2.488	+0.473	<.001	<.001	3	6
LSCC	LOXL2 →	+1.307	+0.439	<.001	<.001	3	6
LSCC	PPFIBP1 →	+0.716	+0.322	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,205 associations by consensus.

UGGT2 vs CD276 — COAD

Explore this scatter interactively →