UGGT1

Across TCGA cell cohorts, UGGT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,509 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UGGT1-associated GO terms across cancer lineages are 'de novo' post-translational protein folding, Glycoprotein biosynthetic process, and Endosomal transport. Each is linked with UGGT1 in more than 18 cancer types. Because this analysis shows association rather than direction, both UGGT1-to-partner and partner-to-UGGT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' post-translational protein folding grouped by UGGT1-low versus UGGT1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGGT1→partner) and Y-score (partner→UGGT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	'de novo' post-translational protein folding →	+0.293	+0.833	<.001	<.001	3	19
BONE	Glycoprotein biosynthetic process →	+0.058	+1.114	<.001	<.001	3	15
BONE	Endosomal transport →	+0.066	+0.946	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to vacuole →	+0.075	+0.659	<.001	<.001	3	13
BONE	Endoplasmic reticulum to cytosol transport →	+0.139	+1.049	.001	<.001	2	14
BONE	Viral gene expression →	+0.098	+0.794	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,509 associations by consensus.

'de novo' post-translational protein folding by UGGT1 expression — LIVER

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