UGDH

Across TCGA patient cohorts, UGDH protein abundance is significantly associated with the RNA expression of many other genes, with 13,326 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible UGDH-associated genes across cancer lineages are TRIM16L, SMIM14, and GSR. Each is linked with UGDH in more than 4 cancer types. Because this analysis shows association rather than direction, both UGDH-to-partner and partner-to-UGDH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UGDH versus TRIM16L in LSCC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGDH→partner) and Y-score (partner→UGDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIM16L →	+1.589	+0.680	<.001	<.001	3	5
BRCA	SMIM14 →	+1.383	+0.962	<.001	<.001	3	5
UCEC	GSR →	+1.136	+0.723	<.001	<.001	3	5
LSCC	PTGR1 →	+1.742	+0.822	<.001	<.001	3	5
LSCC	AKR1B10 →	+3.710	+0.874	<.001	<.001	3	5
LUAD	TSKU →	+0.758	+0.678	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,326 associations by consensus.

UGDH vs TRIM16L — LSCC

Explore this scatter interactively →