UGCG

Across TCGA pan-cancer cohorts, UGCG mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated UGCG data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher UGCG mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UGCG expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and COAD are the cancer types where UGCG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.965	0.447	.002	18	view →
HNSC	DFS	Median	III,IV	1.000	0.861	.003	17	view →
COAD	DFS	Median	III,IV	1.000	0.891	.048	6	view →
PDAC	OS	Quartile	II,III,IV	0.845	0.477	.022	6	view →
LSCC	OS	Median	III,IV	0.506	0.866	.019	3	view →
LUAD	DFS	Median	II,III,IV	1.000	0.798	.015	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

UGCG–CCRCC (DFS)

Open the CCRCC breakdown →