UGCG

Across TCGA patient cohorts, UGCG mutation is significantly associated with the RNA expression of many other genes, with 145 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UGCG-associated genes across cancer lineages are LINC02143, LRRC10, and SNORA70H. Each is linked with UGCG in more than 1 cancer types. Because this analysis shows association rather than direction, both UGCG-to-partner and partner-to-UGCG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02143 grouped by UGCG-low versus UGCG-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGCG→partner) and Y-score (partner→UGCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02143 →	+0.084	+4.867	<.001	.005	3	2
SKCM	LRRC10 →	+0.023	+4.875	.001	.002	3	2
SKCM	SNORA70H →	+0.273	+4.513	<.001	.009	3	2
UCEC	KIR3DL1 →	+0.260	+2.601	<.001	.008	3	1
UCEC	SEPTIN1 →	+1.011	+3.480	<.001	.002	3	1
UCEC	C9orf139 →	+0.306	+3.249	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 145 associations by consensus.

LINC02143 by UGCG expression — SKCM

Explore this box plot interactively →