UGCG

Across TCGA patient cohorts, UGCG mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UGCG-associated genes across cancer lineages are Syk, TFRC, and 14-3-3_zeta. Each is linked with UGCG in more than 1 cancer types. Because this analysis shows association rather than direction, both UGCG-to-partner and partner-to-UGCG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Syk grouped by UGCG-low versus UGCG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGCG→partner) and Y-score (partner→UGCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Syk →	+0.575	+2.183	.003	.035	3	1
UCEC	TFRC →	+0.612	+3.321	.027	.010	3	1
UCEC	14-3-3_zeta →	+0.237	+2.196	.028	.034	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Syk by UGCG expression — UCEC

Explore this box plot interactively →