UFSP2

Across TCGA cell cohorts, UFSP2 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UFSP2-associated genes across cancer lineages are OR11H2, CLEC14A, and KCNH7. Each is linked with UFSP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UFSP2-to-partner and partner-to-UFSP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H2 grouped by UFSP2-low versus UFSP2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UFSP2→partner) and Y-score (partner→UFSP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR11H2 →	+0.023	+3.927	<.001	.004	3	2
BLOOD_Lymphoma	CLEC14A →	+0.694	+3.954	<.001	.005	3	1
BLOOD_Lymphoma	KCNH7 →	+0.989	+4.505	<.001	.003	3	1
BLOOD_Lymphoma	OR6C76 →	+0.037	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	ALKAL1 →	+0.074	+3.714	<.001	.006	3	1
BLOOD_Lymphoma	GSTA2 →	+0.010	+4.169	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

OR11H2 by UFSP2 expression — BLOOD_Lymphoma

Explore this box plot interactively →