UFC1

Across TCGA pan-cancer cohorts, UFC1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UFC1 data layer compared with 19 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher UFC1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UFC1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

PDAC, LSCC, and UCEC are the cancer types where UFC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.467	0.285	.007	34	view →
LSCC	OS	Quartile	II,III,IV	0.505	0.887	.013	11	view →
UCEC	DFS	Tertile	All	0.974	0.832	.031	2	view →
LUAD	DFS	Quartile	II,III,IV	0.373	0.633	.033	2	view →
CCRCC	DFS	Tertile	All	0.626	1.000	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UFC1–PDAC (OS)

Open the PDAC breakdown →