UEVLD

Across TCGA pan-cancer cohorts, UEVLD mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated UEVLD data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher UEVLD mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UEVLD expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, HNSC, and GBM are the cancer types where UEVLD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.695	0.460	.005	28	view →
HNSC	DFS	Quartile	IV	0.890	0.474	.002	13	view →
GBM	DFS	Tertile	All	0.600	0.815	.003	11	view →
CCRCC	DFS	Quartile	III,IV	0.465	0.815	.014	6	view →
LUAD	OS	Tertile	All	0.628	0.846	.027	5	view →
LSCC	DFS	Median	III,IV	1.000	0.867	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

UEVLD–PDAC (OS)

Open the PDAC breakdown →