UEVLD

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UEVLD protein abundance is significantly associated with the RNA expression of many other genes, with 9,618 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible UEVLD-associated genes across cancer lineages are TMEM9B, GTF2H1, and HTATIP2. Each is linked with UEVLD in more than 4 cancer types. Because this analysis shows association rather than direction, both UEVLD-to-partner and partner-to-UEVLD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UEVLD versus TMEM9B in UCEC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UEVLD→partner) and Y-score (partner→UEVLD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTMEM9B →+0.435+0.203<.001<.00135
BRCAGTF2H1 →+0.525+0.376<.001<.00135
LUADHTATIP2 →+0.786+0.243<.001<.00134
UCECPRRG4 →+0.800+0.297<.001<.00134
UCECIDH1 →+0.936+0.230.001<.00134
CCRCCSAA1 →+4.042+0.193<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,618 associations by consensus.

UEVLD vs TMEM9B — UCEC

Per-sample scatter of UEVLD vs TMEM9B in UCEC (Pearson r = 0.36).

Explore this scatter interactively →

Exploration