UEVLD

Across TCGA cell cohorts, UEVLD mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UEVLD-associated genes across cancer lineages are C6orf118, COX6A2, and ITGAD. Each is linked with UEVLD in more than 1 cancer types. Because this analysis shows association rather than direction, both UEVLD-to-partner and partner-to-UEVLD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by UEVLD-low versus UEVLD-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UEVLD→partner) and Y-score (partner→UEVLD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.146	+3.115	<.001	.004	3	1
LARGE_INTESTINE	COX6A2 →	+0.058	+3.700	<.001	.009	3	1
LARGE_INTESTINE	ITGAD →	+0.009	+2.925	.003	.007	3	1
LARGE_INTESTINE	DEFA4 →	+0.022	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	NPY2R →	+0.003	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

C6orf118 by UEVLD expression — LARGE_INTESTINE

Explore this box plot interactively →