UCP3

Across TCGA patient cohorts, UCP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,341 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible UCP3-associated proteins across cancer lineages are HCFC1, PHRF1_S814, and PIEZO1. Each is linked with UCP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both UCP3-to-partner and partner-to-UCP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UCP3 versus HCFC1 in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UCP3→partner) and Y-score (partner→UCP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HCFC1 →	+0.225	+0.301	<.001	<.001	3	5
OV	PHRF1_S814 →	-0.643	-0.575	.009	<.001	3	4
PDAC	PIEZO1 →	-0.394	-0.193	.007	.003	3	4
HNSC	PSIP1 →	+0.534	+0.877	<.001	<.001	3	4
HNSC	PSIP1_S106 →	+0.452	+0.569	<.001	.003	3	4
GBM	TAF6L →	+0.376	+0.497	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,341 associations by consensus.

UCP3 vs HCFC1 — GBM

Explore this scatter interactively →