UCP3

Across TCGA patient cohorts, UCP3 protein abundance is significantly associated with the RNA expression of many other genes, with 357 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible UCP3-associated genes across cancer lineages are MYL9, DKKL1, and MEIS3. Each is linked with UCP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both UCP3-to-partner and partner-to-UCP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UCP3 versus MYL9 in HNSC, with a Pearson correlation of 0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCP3→partner) and Y-score (partner→UCP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MYL9 →	+1.470	+0.704	.001	.009	3	1
HNSC	DKKL1 →	+0.359	+0.704	<.001	.009	3	1
HNSC	MEIS3 →	+1.285	+0.704	.001	.009	3	1
HNSC	UNC93A →	-2.445	-0.990	<.001	.001	3	1
HNSC	CALD1 →	+1.765	+0.880	.003	.008	3	1
HNSC	RASSF8 →	+1.103	+0.704	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 357 associations by consensus.

UCP3 vs MYL9 — HNSC

Explore this scatter interactively →