UCP2

Across TCGA patient cohorts, UCP2 protein abundance is significantly associated with the RNA expression of many other genes, with 267 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UCP2-associated genes across cancer lineages are SERPINA4, ATP11C, and STARD3NL. Each is linked with UCP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UCP2-to-partner and partner-to-UCP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UCP2 versus SERPINA4 in LUAD, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCP2→partner) and Y-score (partner→UCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SERPINA4 →	+0.692	+0.608	.003	.002	3	1
LUAD	ATP11C →	-0.701	-0.659	.002	<.001	3	1
LUAD	STARD3NL →	-0.744	-0.753	.001	.004	3	1
LUAD	PDE4C →	-0.145	-0.753	.009	.006	3	1
LUAD	AP1S1 →	-0.966	-0.922	.006	.004	3	1
LUAD	AGR2 →	+2.386	+0.557	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 267 associations by consensus.

UCP2 vs SERPINA4 — LUAD

Explore this scatter interactively →