Across TCGA patient cohorts, UCKL1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,790 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible UCKL1-associated genes across cancer lineages are UPRT, RASGRF2, and FEZ1. Each is linked with UCKL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both UCKL1-to-partner and partner-to-UCKL1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCKL1→partner) and Y-score (partner→UCKL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UPRT →	+0.392	+0.217	<.001	<.001	3	4
BRCA	RASGRF2 →	-0.768	-0.184	<.001	.002	3	4
GBM	FEZ1 →	-0.588	-0.190	.002	<.001	3	4
LUAD	RASA4 →	-0.199	-0.118	.004	.002	2	4
CCRCC	CCDC102B →	-0.709	-0.148	<.001	.002	3	3
PDAC	ZNF25 →	-0.314	-0.259	.007	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,790 associations by consensus.

Exploration

UCKL1 survival (RNA) · tumor vs normal (RNA) · all UCKL1 data types