UCK2

Across TCGA patient cohorts, UCK2 mutation is significantly associated with the RNA expression of many other genes, with 2,233 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UCK2-associated genes across cancer lineages are RNA5SP401, RN7SL248P, and RNU6-1214P. Each is linked with UCK2 in more than 2 cancer types. Because this analysis shows association rather than direction, both UCK2-to-partner and partner-to-UCK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP401 grouped by UCK2-low versus UCK2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCK2→partner) and Y-score (partner→UCK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP401 →	+0.178	+2.635	<.001	.004	3	3
UCEC	RN7SL248P →	+0.046	+2.847	<.001	.008	3	2
CESC	RNU6-1214P →	+0.530	+5.306	<.001	.006	3	2
CESC	OR5G5P →	+0.127	+5.201	<.001	.007	3	2
BRCA	LINC01646 →	+0.089	+6.215	<.001	.001	3	2
SKCM	E2F6P1 →	+0.043	+4.594	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,233 associations by consensus.

RNA5SP401 by UCK2 expression — UCEC

Explore this box plot interactively →