UCHL1

Across TCGA patient cohorts, UCHL1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,289 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UCHL1-associated genes across cancer lineages are TMCC2, B4GALNT1, and PNMA8A. Each is linked with UCHL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both UCHL1-to-partner and partner-to-UCHL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UCHL1 versus TMCC2 in GBM, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCHL1→partner) and Y-score (partner→UCHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TMCC2 →	+1.170	+0.738	<.001	<.001	3	8
LSCC	B4GALNT1 →	+1.040	+1.175	<.001	<.001	3	8
OV	PNMA8A →	+1.046	+1.042	.002	<.001	3	7
HNSC	MLLT11 →	+1.318	+1.549	<.001	<.001	3	7
UCEC	ARHGEF25 →	+0.632	+1.045	<.001	<.001	3	7
GBM	NXPE3 →	+0.644	+0.515	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,289 associations by consensus.

UCHL1 vs TMCC2 — GBM

Explore this scatter interactively →