UCHL1-AS1

Across TCGA pan-cancer cohorts, UCHL1-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated UCHL1-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher UCHL1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UCHL1-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUSC show a favorable association.

MESO, READ, and PAAD are the cancer types where UCHL1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Quartile	III,IV	0.222	0.424	.001	57	view →
READ	OS	Tertile	All	0.393	0.921	<.001	54	view →
PAAD	OS	Tertile	All	0.747	0.309	<.001	45	view →
UCEC	DFS	Tertile	All	0.822	0.913	<.001	30	view →
KICH	DFS	Median	II,III,IV	0.422	0.928	.009	24	view →
THCA	OS	Tertile	All	0.730	0.938	.019	24	view →
THYM	DFS	Tertile	II,III,IV	0.406	0.774	.033	12	view →
KIRC	DFS	Tertile	All	0.351	0.654	.017	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
UVM	OS	Tertile	III,IV	0.241	0.765	.002	9	view →
LUSC	OS	Median	II,III,IV	0.710	0.342	.013	8	view →
BLCA	OS	Tertile	IV	0.784	0.316	.042	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

UCHL1-AS1–MESO (DFS)

Open the MESO breakdown →