UCHL1-AS1

Across TCGA pan-cancer cohorts, UCHL1-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of UCHL1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where UCHL1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UCHL1-AS1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

HNSC, LUAD, and KIRC are the cancer types where UCHL1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UCHL1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.068	.007	6	view →
LUAD	Male	All	+0.131	.007	3	view →
KIRC	All	All	−0.021	.033	2	view →
KICH	All	All	+0.094	.044	1	view →
STAD	Male	All	+0.016	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

UCHL1-AS1–HNSC

Open the HNSC breakdown →