UBXN6

Across TCGA patient cohorts, UBXN6 mutation is significantly associated with the RNA expression of many other genes, with 887 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBXN6-associated genes across cancer lineages are IGHVII-67-1, RNU6-366P, and RNU6-739P. Each is linked with UBXN6 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN6-to-partner and partner-to-UBXN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHVII-67-1 grouped by UBXN6-low versus UBXN6-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN6→partner) and Y-score (partner→UBXN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	IGHVII-67-1 →	+0.542	+7.977	<.001	.007	3	2
UCEC	RNU6-366P →	+0.205	+3.351	<.001	.004	3	2
UCEC	RNU6-739P →	+0.203	+2.977	.002	.009	3	2
UCEC	RN7SL812P →	+0.412	+3.032	.001	.002	3	2
BRCA	H3P46 →	+0.193	+7.731	<.001	.009	3	1
BLCA	NDUFB9P3 →	+0.051	+4.296	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 887 associations by consensus.

IGHVII-67-1 by UBXN6 expression — LGG

Explore this box plot interactively →