UBXN4

Across TCGA patient cohorts, UBXN4 mutation is significantly associated with the RNA expression of many other genes, with 1,774 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBXN4-associated genes across cancer lineages are CRLF3P2, ATP5F1B, and RNA5SP210. Each is linked with UBXN4 in more than 2 cancer types. Because this analysis shows association rather than direction, both UBXN4-to-partner and partner-to-UBXN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRLF3P2 grouped by UBXN4-low versus UBXN4-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN4→partner) and Y-score (partner→UBXN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CRLF3P2 →	+0.038	+5.044	.008	.009	3	3
UCEC	ATP5F1B →	+0.566	+3.708	.004	<.001	3	3
LUSC	RNA5SP210 →	+0.250	+2.677	.002	.003	3	3
HNSC	E2F6P1 →	+0.046	+5.178	<.001	.002	3	3
UCEC	RN7SL650P →	+0.284	+2.233	.002	.001	3	2
UCEC	RNA5SP412 →	+0.654	+2.315	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,774 associations by consensus.

CRLF3P2 by UBXN4 expression — LUAD

Explore this box plot interactively →