UBXN2A

Across TCGA patient cohorts, UBXN2A mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBXN2A-associated genes across cancer lineages are CENPVL1, RNU6-1213P, and RPL21P109. Each is linked with UBXN2A in more than 2 cancer types. Because this analysis shows association rather than direction, both UBXN2A-to-partner and partner-to-UBXN2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPVL1 grouped by UBXN2A-low versus UBXN2A-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN2A→partner) and Y-score (partner→UBXN2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CENPVL1 →	+0.024	+7.954	<.001	.008	3	3
UCEC	RNU6-1213P →	+0.430	+5.140	<.001	<.001	3	2
SKCM	RPL21P109 →	+0.064	+3.766	.002	.005	3	1
SKCM	RN7SL164P →	+0.072	+4.328	<.001	.007	3	1
SKCM	RN7SL424P →	+0.060	+4.328	.002	.007	3	1
BRCA	RN7SKP228 →	+0.452	+5.259	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

CENPVL1 by UBXN2A expression — HNSC

Explore this box plot interactively →