UBXN2A

Across TCGA cell cohorts, UBXN2A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,236 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBXN2A-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Positive regulation of mitochondrial ATP synthesis coupled electron transport, and Nucleus organization. Each is linked with UBXN2A in more than 14 cancer types. Because this analysis shows association rather than direction, both UBXN2A-to-partner and partner-to-UBXN2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by UBXN2A-low versus UBXN2A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN2A→partner) and Y-score (partner→UBXN2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of cell cycle process →	+0.073	+0.816	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.156	+1.097	<.001	<.001	3	15
BREAST	Nucleus organization →	+0.062	+0.609	.001	.002	2	15
BREAST	Regulation of metaphase/anaphase transition of cell cycle →	+0.119	+0.912	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.095	+0.825	.003	.001	3	13
BREAST	Cell division →	+0.079	+0.573	<.001	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,236 associations by consensus.

Negative regulation of cell cycle process by UBXN2A expression — BREAST

Explore this box plot interactively →