UBXN10

Across TCGA pan-cancer cohorts, UBXN10 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated UBXN10 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UBXN10 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBXN10 expression acts as an unfavorable survival marker, although some lineages such as LSCC and UCEC show a favorable association.

LUAD, LSCC, and UCEC are the cancer types where UBXN10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	III,IV	0.314	0.854	.003	17	view →
LSCC	DFS	Median	All	0.868	0.446	.009	12	view →
UCEC	DFS	Tertile	All	0.963	0.799	.020	8	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

UBXN10–LUAD (DFS)

Open the LUAD breakdown →