UBXN10

Across TCGA pan-cancer cohorts, UBXN10 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of UBXN10’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where UBXN10 RNA is repressed in tumor relative to normal tissue. In most cancer types UBXN10 is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

LUSC, KICH, and KIRC are the cancer types where UBXN10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBXN10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	II,III,IV	−2.611	<.001	8	view →
KICH	Male	All	−1.062	<.001	7	view →
KIRC	All	All	+0.345	.003	3	view →
PAAD	All	All	+1.975	.012	2	view →
LIHC	Female	II,III,IV	−1.234	.003	2	view →
PRAD	All	All	−1.223	<.001	2	view →
HNSC	Male	All	−0.430	.020	2	view →
THCA	All	All	−0.430	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

UBXN10–LUSC

Open the LUSC breakdown →