UBXN10

Across TCGA cell cohorts, UBXN10 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBXN10-associated genes across cancer lineages are TTLL8, ELOA3DP, and IQCF6. Each is linked with UBXN10 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN10-to-partner and partner-to-UBXN10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTLL8 grouped by UBXN10-low versus UBXN10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN10→partner) and Y-score (partner→UBXN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TTLL8 →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	ELOA3DP →	+0.039	+4.273	<.001	.006	3	1
LARGE_INTESTINE	IQCF6 →	+0.346	+4.467	<.001	.004	3	1
BLOOD_Leukemia	LGI1 →	+0.129	+5.539	<.001	.003	3	1
BLOOD_Leukemia	C20orf85 →	+0.032	+5.969	<.001	.001	3	1
BLOOD_Leukemia	USP29 →	+0.006	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TTLL8 by UBXN10 expression — LARGE_INTESTINE

Explore this box plot interactively →