UBXN1

Across TCGA patient cohorts, UBXN1 mutation is significantly associated with the RNA expression of many other genes, with 527 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBXN1-associated genes across cancer lineages are OR6K1P, ATG4AP1, and RN7SKP12. Each is linked with UBXN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN1-to-partner and partner-to-UBXN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6K1P grouped by UBXN1-low versus UBXN1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN1→partner) and Y-score (partner→UBXN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR6K1P →	+0.159	+5.182	<.001	.001	3	2
HNSC	ATG4AP1 →	+0.100	+4.822	<.001	.006	3	2
HNSC	RN7SKP12 →	+0.208	+5.339	<.001	.003	3	2
HNSC	RNU6-1137P →	+0.581	+6.090	<.001	<.001	3	2
HNSC	BCAR1P1 →	+0.233	+4.346	<.001	.007	3	2
HNSC	MIR5707 →	+0.374	+4.822	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 527 associations by consensus.

OR6K1P by UBXN1 expression — HNSC

Explore this box plot interactively →