UBXN1

Across TCGA cell cohorts, UBXN1 mutation is significantly associated with the mutation status of many other genes, with 2,114 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBXN1-associated genes across cancer lineages are SYNJ2, PLK3, and MICAL3. Each is linked with UBXN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN1-to-partner and partner-to-UBXN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SYNJ2 grouped by UBXN1-low versus UBXN1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN1→partner) and Y-score (partner→UBXN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SYNJ2 →	+4.297	+4.857	.009	.009	1	2
BREAST	PLK3 →	+4.297	+4.857	.009	.009	1	2
BREAST	MICAL3 →	+5.297	+5.297	.004	.004	1	2
LARGE_INTESTINE	GBP4 →	+4.087	+5.044	.001	.001	1	2
LARGE_INTESTINE	ZNF326 →	+3.087	+4.392	.005	.005	1	2
LARGE_INTESTINE	MON1A →	+3.087	+4.392	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,114 associations by consensus.

SYNJ2 by UBXN1 expression — BREAST

Explore this box plot interactively →