UBTFL1

Across TCGA patient cohorts, UBTFL1 mutation is significantly associated with the RNA expression of many other genes, with 1,892 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBTFL1-associated genes across cancer lineages are LINC02564, OR7G2, and OR1M1. Each is linked with UBTFL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both UBTFL1-to-partner and partner-to-UBTFL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02564 grouped by UBTFL1-low versus UBTFL1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBTFL1→partner) and Y-score (partner→UBTFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC02564 →	+0.080	+4.308	<.001	.009	3	3
SARC	OR7G2 →	+0.085	+5.345	<.001	.005	3	2
SARC	OR1M1 →	+0.062	+5.620	.001	.004	3	2
SARC	MIR1183 →	+0.531	+5.345	<.001	.005	3	2
SARC	RAC1P6 →	+0.160	+7.988	<.001	<.001	3	2
SARC	OTX2P2 →	+0.174	+6.380	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,892 associations by consensus.

LINC02564 by UBTFL1 expression — COAD

Explore this box plot interactively →