UBTF

Across TCGA patient cohorts, UBTF RNA expression is significantly associated with the protein abundance of many other proteins, with 19,428 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBTF-associated proteins across cancer lineages are GATAD2B, UBR7, and VEZF1. Each is linked with UBTF in more than 5 cancer types. Because this analysis shows association rather than direction, both UBTF-to-partner and partner-to-UBTF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBTF versus GATAD2B in GBM, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBTF→partner) and Y-score (partner→UBTF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GATAD2B →	+0.334	+0.350	<.001	<.001	3	6
LSCC	UBR7 →	+0.464	+0.498	<.001	<.001	3	5
BRCA	VEZF1 →	+0.443	+0.393	<.001	<.001	3	5
LSCC	SNW1 →	+0.192	+0.357	<.001	<.001	3	5
LSCC	RRBP1 →	-0.444	-0.485	<.001	<.001	3	5
BRCA	GALK2 →	-0.280	-0.383	.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,428 associations by consensus.

UBTF vs GATAD2B — GBM

Explore this scatter interactively →