UBTF

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, UBTF RNA expression is significantly associated with the go_rna of many other GO terms, with 5,437 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UBTF-associated GO terms across cancer lineages are Nuclear export, Positive regulation of nuclear cell cycle DNA replication, and Nucleic acid transport. Each is linked with UBTF in more than 19 cancer types. Because this analysis shows association rather than direction, both UBTF-to-partner and partner-to-UBTF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear export grouped by UBTF-low versus UBTF-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBTF→partner) and Y-score (partner→UBTF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHNuclear export →+0.114+0.872<.001.003320
BONEPositive regulation of nuclear cell cycle DNA replication →+0.152+0.943.001<.001320
BONENucleic acid transport →+0.126+1.039.002<.001319
BONERNA transport →+0.126+1.039.002<.001319
BONEEstablishment of RNA localization →+0.123+0.990.002.001319
BONERNA localization →+0.120+0.883.004.004319
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,437 associations by consensus.

Nuclear export by UBTF expression — STOMACH

Box plot of Nuclear export in UBTF-low vs UBTF-high samples in STOMACH.

Explore this box plot interactively →

Exploration