UBR1

Across TCGA patient cohorts, UBR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,080 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible UBR1-associated proteins across cancer lineages are DNAJC17, HDGFL3, and NDUFAF7. Each is linked with UBR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both UBR1-to-partner and partner-to-UBR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBR1 versus DNAJC17 in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBR1→partner) and Y-score (partner→UBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DNAJC17 →	+0.346	+0.426	<.001	<.001	3	7
BRCA	HDGFL3 →	+0.495	+0.418	<.001	.001	3	5
OV	NDUFAF7 →	-0.339	-0.582	.001	<.001	3	5
OV	PARVA →	+0.405	+0.750	<.001	<.001	3	5
LSCC	PPIF →	-0.551	-0.490	<.001	<.001	3	5
LUAD	TJP1_S912 →	+0.758	+0.327	<.001	.004	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,080 associations by consensus.

UBR1 vs DNAJC17 — HNSC

Explore this scatter interactively →