UBQLN1

Across TCGA patient cohorts, UBQLN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,154 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UBQLN1-associated proteins across cancer lineages are WDR5, ANP32B, and RAD23B. Each is linked with UBQLN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both UBQLN1-to-partner and partner-to-UBQLN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBQLN1 versus WDR5 in LSCC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UBQLN1→partner) and Y-score (partner→UBQLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR5 →	+0.272	+0.525	<.001	<.001	3	7
LSCC	ANP32B →	+0.372	+0.496	<.001	<.001	3	7
BRCA	RAD23B →	+0.262	+0.362	<.001	.001	3	6
PDAC	FUBP3 →	+0.203	+0.331	<.001	<.001	3	6
OV	TRAF2 →	+0.348	+0.470	<.001	<.001	3	6
LSCC	PRRC2B →	+0.281	+0.370	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,154 associations by consensus.

UBQLN1 vs WDR5 — LSCC

Explore this scatter interactively →