UBQLN1

Across TCGA cell cohorts, UBQLN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,102 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBQLN1-associated GO terms across cancer lineages are Positive regulation of mRNA 3'-end processing, Immunoglobulin heavy chain V-D-J recombination, and Negative regulation of calcium ion transmembrane transporter activity. Each is linked with UBQLN1 in more than 18 cancer types. Because this analysis shows association rather than direction, both UBQLN1-to-partner and partner-to-UBQLN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA 3'-end processing grouped by UBQLN1-low versus UBQLN1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBQLN1→partner) and Y-score (partner→UBQLN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of mRNA 3'-end processing →	+0.152	+0.803	.001	.001	3	19
URINARY_TRACT	Immunoglobulin heavy chain V-D-J recombination →	+0.183	+0.706	.004	<.001	3	17
LUNG_NSCLC_LUSC	Negative regulation of calcium ion transmembrane transporter activity →	+0.134	+0.821	<.001	.001	3	15
BLOOD_Leukemia	Transcription elongation-coupled chromatin remodeling →	+0.113	+0.849	<.001	<.001	3	14
BLOOD_Leukemia	Positive regulation of RNA splicing →	+0.077	+0.484	<.001	<.001	3	14
PANCREAS	mRNA export from nucleus →	+0.101	+0.901	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,102 associations by consensus.

Positive regulation of mRNA 3'-end processing by UBQLN1 expression — OESOPHAGUS

Explore this box plot interactively →