UBLCP1

Across TCGA cell cohorts, UBLCP1 mutation is significantly associated with the mutation status of many other genes, with 2,885 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBLCP1-associated genes across cancer lineages are KCND2, MYOF, and ITPR3. Each is linked with UBLCP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both UBLCP1-to-partner and partner-to-UBLCP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCND2 grouped by UBLCP1-low versus UBLCP1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBLCP1→partner) and Y-score (partner→UBLCP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KCND2 →	+4.014	+4.969	.008	.008	1	3
LARGE_INTESTINE	MYOF →	+1.824	+3.184	<.001	<.001	1	3
LARGE_INTESTINE	ITPR3 →	+1.824	+3.184	<.001	<.001	1	2
BLOOD_Lymphoma	GRIK2 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	NEUROD6 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	TRPV6 →	+6.014	+6.014	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,885 associations by consensus.

KCND2 by UBLCP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →