UBLCP1

Across TCGA pan-cancer cohorts, UBLCP1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of UBLCP1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where UBLCP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBLCP1 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

HNSC, LIHC, and KICH are the cancer types where UBLCP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBLCP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	+0.480	<.001	11	view →
LIHC	Male	II,III,IV	+1.045	<.001	9	view →
KICH	All	All	−0.843	<.001	5	view →
CHOL	Male	All	+1.875	<.001	3	view →
KIRP	All	IV	+0.590	.005	2	view →
UCEC	All	All	−0.495	.035	2	view →
ESCA	All	II,III,IV	+0.484	.044	2	view →
LUSC	All	III,IV	−0.384	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

UBLCP1–HNSC

Open the HNSC breakdown →