UBLCP1

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, UBLCP1 mutation is significantly associated with the drug of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBLCP1-associated genes across cancer lineages are CCT007093, SGC-CBP30, and 50869. Each is linked with UBLCP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBLCP1-to-partner and partner-to-UBLCP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCT007093 grouped by UBLCP1-low versus UBLCP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBLCP1→partner) and Y-score (partner→UBLCP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECCT007093 →+0.319+2.649.032.04631
LARGE_INTESTINESGC-CBP30 →+0.293+2.649.038.04631
LARGE_INTESTINE50869 →+0.426+2.649.044.04631
LARGE_INTESTINE729189 →+0.310+2.649.014.04631
LARGE_INTESTINEIspinesib Mesylate →+0.653+2.652.046.04531
LARGE_INTESTINEQuizartinib →+0.496+2.652.001.04531
Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

CCT007093 by UBLCP1 expression — LARGE_INTESTINE

Box plot of CCT007093 in UBLCP1-low vs UBLCP1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration