UBL7

Across TCGA patient cohorts, UBL7 mutation is significantly associated with the RNA expression of many other genes, with 259 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible UBL7-associated genes across cancer lineages are RNU6-373P, RNU6-494P, and RNU5E-10P. Each is linked with UBL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBL7-to-partner and partner-to-UBL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-373P grouped by UBL7-low versus UBL7-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBL7→partner) and Y-score (partner→UBL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-373P →	+1.375	+4.693	<.001	.007	3	2
COAD	RNU6-494P →	+1.405	+4.237	<.001	.008	3	2
UCEC	RNU5E-10P →	+0.596	+3.043	.007	.003	3	2
UCEC	RNU6-933P →	+0.489	+3.184	.005	.001	3	2
UCEC	RNU6-892P →	+0.602	+3.026	.006	.005	3	2
UCEC	RNU6-1077P →	+0.494	+2.925	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 259 associations by consensus.

RNU6-373P by UBL7 expression — COAD

Explore this box plot interactively →