Across TCGA patient cohorts, UBL4B mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBL4B-associated genes across cancer lineages are Gab2, Rad50, and Cyclin-E2. Each is linked with UBL4B in more than 1 cancer types. Because this analysis shows association rather than direction, both UBL4B-to-partner and partner-to-UBL4B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBL4B→partner) and Y-score (partner→UBL4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Gab2 →	+0.411	+3.584	.017	.002	3	1
UCEC	Rad50 →	-0.234	-2.459	.045	.020	3	1
UCEC	Cyclin-E2 →	+0.220	+2.459	.006	.020	3	1
UCEC	Tuberin →	+0.342	+3.009	.008	.019	2	1
UCEC	cIAP →	+0.168	+2.486	.011	.011	2	1
UCEC	Annexin_VII →	-0.160	-3.584	.017	.002	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

UBL4B survival (RNA) · tumor vs normal (RNA) · all UBL4B data types