Across TCGA pan-cancer cohorts, UBL4B RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated UBL4B data layer.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher UBL4B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated UBL4B expression acts as an unfavorable survival marker, although some lineages such as CESC and STAD show a favorable association.
ACC, THCA, and KIRP are the cancer types where UBL4B RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.