UBFD1

Across TCGA pan-cancer cohorts, UBFD1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UBFD1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher UBFD1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated UBFD1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where UBFD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	III,IV	0.651	0.890	.014	14	view →
LUAD	DFS	Tertile	II,III,IV	0.616	0.299	.021	12	view →
LSCC	DFS	Quartile	III,IV	0.383	0.894	.017	10	view →
PDAC	OS	Median	IV	0.951	0.381	.006	9	view →
GBM	OS	Median	All	0.256	0.509	.002	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UBFD1–CCRCC (OS)

Open the CCRCC breakdown →