UBFD1

Across TCGA pan-cancer cohorts, UBFD1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of UBFD1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where UBFD1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UBFD1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRP, COAD, and HNSC are the cancer types where UBFD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UBFD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	IV	+1.225	<.001	11	view →
COAD	Female	II,III,IV	+0.981	<.001	11	view →
HNSC	All	III,IV	+0.682	<.001	10	view →
LUAD	Male	III,IV	+1.484	<.001	9	view →
LIHC	All	III,IV	+1.004	<.001	9	view →
BLCA	All	All	+0.726	<.001	9	view →
STAD	Male	II,III,IV	+1.042	<.001	8	view →
LUSC	Male	II,III,IV	+0.875	<.001	7	view →
READ	All	All	+0.818	<.001	7	view →
BRCA	All	II,III,IV	+0.711	<.001	6	view →
CHOL	Female	All	+2.329	<.001	5	view →
ESCA	All	II,III,IV	+0.920	.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

UBFD1–KIRP

Open the KIRP breakdown →