UBFD1

Across TCGA cell cohorts, UBFD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,665 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBFD1-associated GO terms across cancer lineages are DNA-templated transcription initiation, Nucleic acid catabolic process, and Regulation of nucleotide-excision repair. Each is linked with UBFD1 in more than 16 cancer types. Because this analysis shows association rather than direction, both UBFD1-to-partner and partner-to-UBFD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by UBFD1-low versus UBFD1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBFD1→partner) and Y-score (partner→UBFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.100	+1.455	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Nucleic acid catabolic process →	+0.061	+1.292	<.001	<.001	3	15
STOMACH	Regulation of nucleotide-excision repair →	+0.155	+0.990	.002	.004	3	15
BREAST	Symbiont-mediated disruption of host cell PML body →	+0.133	+1.037	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Negative regulation of autophagosome maturation →	+0.105	+0.827	<.001	<.001	3	14
LUNG_SCLC	Nuclear export →	+0.093	+0.722	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,665 associations by consensus.

DNA-templated transcription initiation by UBFD1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →