UBE4A

Across TCGA patient cohorts, UBE4A protein abundance is significantly associated with the RNA expression of many other genes, with 9,231 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible UBE4A-associated genes across cancer lineages are C11orf71, ZPR1, and STT3A. Each is linked with UBE4A in more than 6 cancer types. Because this analysis shows association rather than direction, both UBE4A-to-partner and partner-to-UBE4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBE4A versus C11orf71 in HNSC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBE4A→partner) and Y-score (partner→UBE4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	C11orf71 →	+0.792	+0.244	<.001	<.001	3	7
OV	ZPR1 →	+0.545	+0.356	<.001	<.001	3	6
HNSC	STT3A →	+0.541	+0.282	<.001	<.001	3	6
HNSC	DLAT →	+0.709	+0.298	<.001	<.001	2	7
HNSC	MPZL3 →	+0.917	+0.252	<.001	<.001	3	6
OV	VPS11 →	+0.468	+0.265	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,231 associations by consensus.

UBE4A vs C11orf71 — HNSC

Explore this scatter interactively →